Table 7.

Effect of LI12542F6 supplementation on the hematology and serum clinical chemistry parameters of the participants

	Parameters	Evaluations	Placebo (n = 20)	LI12542F6 (n = 20)
Hematology	Hemoglobin (g/dL)	Screening	14.52 ± 0.82	14.66 ± 0.94
		Day 56	14.69 ± 0.96	14.74 ± 0.85
	Platelet count (105/μL)	Screening	2.70 ± 0.64	2.33 ± 0.57
		Day 56	2.69 ± 0.59	2.55 ± 0.41
	Red blood cell (106/μL)	Screening	5.59 ± 0.75	5.38 ± 0.35
		Day 56	5.39 ± 0.37	5.18 ± 0.36
	Total white blood cells (/μL)	Screening	7,040 ± 1,377	7,580 ± 1,278
		Day 56	7,520 ± 1,586	7,345 ± 1,414
	Neutrophils (%)	Screening	61.95 ± 6.43	62.95 ± 7.00
		Day 56	69.0 5 ± 6.21*	62.40 ± 5.94#
	Lymphocytes (%)	Screening	31.45 ± 5.97	30.10 ± 6.50
		Day 56	24.85 ± 4.79*	31.60 ± 5.76#
	Eosinophil (%)	Screening	2.8 5 ± 1.81	3.20 ± 1.94
		Day 56	3.50 ± 2.48	2.80 ± 1.20
	Monocytes (%)	Screening	3.80 ± 0.52	3.75 ± 0.55
		Day 56	3.00 ± 1.38*	3.15 ± 1.04*
	Basophils (%)	Screening	0.00 ± 0.00	0.00 ± 0.00
		Day 56	0.00 ± 0.00	0.05 ± 0.22
Serum clinical chemistry	Fasting glucose (mg/dL)	Screening	73.75 ± 7.75	78.55 ± 7.34
		Day 56	88.25 ± 7.98*	88.40 ± 8.41*
	Creatinine (mg/dL)	Screening	0.76 ± 0.14	0.77 ± 0.12
		Day 56	0.85 ± 0.11*	0.89 ± 0.11*
	Blood urea nitrogen (mg/dL)	Screening	10.10 ± 2.88	10.20 ± 2.76
		Day 56	10.40 ± 2.72	11.05 ± 2.87
	Bilirubin (mg/dL)	Screening	0.65 ± 0.34	0.58 ± 0.17
		Day 56	0.70 ± 0.28	0.66 ± 0.23
	Aspartate transaminase (U/L)	Screening	29.05 ± 7.20	27.50 ± 8.82
		Day 56	27.35 ± 6.96	26.00 ± 5.86
	Alanine transaminase (U/L)	Screening	27.75 ± 6.38	29.85 ± 11.73
		Day 56	28.45 ± 10.22	25.55 ± 8.70*
	Alkaline phosphate (IU/L)	Screening	85.90 ± 16.68	86.25 ± 20.90
		Day 56	91.20 ± 17.29	86.30 ± 16.57
	Sodium (mEq/L)	Screening	139.60 ± 2.46	139.15 ± 1.09
		Day 56	140.15 ± 2.16	139.30 ± 1.75
	Potassium (mEq/L)	Screening	4.22 ± 0.25	4.22 ± 0.18
		Day 56	4.26 ± 0.22	4.23 ± 0.23
	Albumin (g/dL)	Screening	4.33 ± 0.24	4.35 ± 0.17
		Day 56	4.42 ± 0.19	4.46 ± 0.25
	Low-density lipoprotein (mg/dL)	Screening	82.00 ± 21.68	86.90 ± 29.54
		Day 56	85.80 ± 21.90	89.20 ± 24.90
	High-density lipoprotein (mg/dL)	Screening	37.90 ± 7.95	42.85 ± 7.27#
		Day 56	39.80 ± 9.56*	41.55 ± 7.13
	Very low-density lipoprotein (mg/dL)	Screening	23.40 ± 11.00	21.95 ± 9.56
		Day 56	27.00 ± 13.67	27.00 ± 12.75*
	Triglyceride (mg/dL)	Screening	118.30 ± 54.32	111.30 ± 47.68
		Day 56	133.50 ± 64.84	135.75 ± 64.32*
	Total cholesterol (mg/dL)	Screening	143.30 ± 24.88	151.70 ± 35.23
		Day 56	152.60 ± 25.65*	157.75 ± 30.89

Data present the mean ± SD.

^*and

^#indicate significance (P < 0.05) in intragroup comparison (vs. baseline) and between-the-groups comparison (vs. placebo), respectively, analyzed using student t-test.