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. 2023 Feb 4;8:9. doi: 10.1038/s41541-023-00604-2

Fig. 4. Serum IgG cross-reactivity to host cardiac and neuronal tissue proteins.

Fig. 4

Serum IgG titre against cardiac myosin (a), tropomyosin (b), laminin (c), tubulin (d) dopamine receptor 1 (e) and 2 (f), and lysoganglioside (g) in rats (n = 6) injected with PBS (•), rM5 (▪), P*17-DT (▴) or K4S2-DT (♦) are shown. Absorbance values of day-35 rat sera at 1:400. Statistical analysis performed by one-way ANOVA with Dunnett multiple comparison. Significance to PBS group, *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001. Error bars represent standard deviation. Serum IgG cross-reactivity to endogenous proteins in lysates of cerebellum and striatum from naive rats (h). MW molecular weight.