Table 15:
Post-Thrombotic Syndrome With Mechanical Thrombectomy Use in Acute and Subacute DVT in Randomized Controlled Trials
| Results | ||||
|---|---|---|---|---|
| Author, year | Outcome measurement | MT | Comparator | P value |
| PMT (AngioJet) | ||||
| ATTRACT trial92 PMT vs. control (no procedure, anticoagulation alone) |
Proportion with post-thrombotic syndrome, 24 mo | 44.0% (n = 33) | 41.4% (n = 79) | P = .69 |
| Iliofemoral subgroupa | 28.1% (n = 9) | 30.3% (n = 20) | P = .82 | |
| Popliteal subgroupa | 37.9% (n = 11) | 42.9% (n = 39) | P = .64 | |
| Vacuum Aspiration (Indigo) | ||||
| No randomized studies met our inclusion criteria for this mechanical thrombectomy device | ||||
| Rotational (Rotarex or Cleaner) | ||||
| No randomized controlled trials met our conclusion criteria for this mechanical thrombectomy device | ||||
| Ultrasound Assisted (EKOS) | ||||
| Engelberger et al, 20152 | Mean Villalta score | 3.0 (SD ± 3.9) | 1.9 (SD ± 1.9) | P = .21 |
| CAVA trial, Notton et al, 20203,102 | Proportion of patients with post-thrombotic syndrome, at final visit, by Villalta score | 30.6% (n = 19) | 44.8% (n = 26) | P = .11 |
Abbreviations: ATTRACT, Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis; DVT, deep vein thrombosis; MT, mechanical thrombectomy; PMT, pharmacomechanical thrombectomy; SD, standard deviation.
a
Per protocol analysis.