Table 17:
Technical Success With Mechanical Thrombectomy Use in Acute and Subacute DVT in Randomized Controlled Trials
| Results | ||||
|---|---|---|---|---|
| Author, year | Outcome measurement | MT | Comparator | P value |
| PMT (AngioJet) | ||||
| ATTRACT trial89,92 (PMT vs. infusion first rtPA) | Post-procedure thrombus score | 1.7 (SD ± 2.8) | 3.1 (SD ± 4.0) | P = .001 |
| Thrombus score change from baseline | 6.7 (SD ± 4.5) | 9.8 (SD ± 6.3) | P < .001 | |
| Proportion with clot lysis > 90% | 75% (n = 56) | 72% (n = 138) | P = .64 | |
| Vacuum Aspiration (Indigo) | ||||
| No randomized studies met our inclusion criteria for this mechanical thrombectomy device | ||||
| Rotational (Rotarex or Cleaner) | ||||
| No randomized controlled trials met our inclusion criteria for this mechanical thrombectomy device | ||||
| Ultrasound Assisted (EKOS) | ||||
| Engelberger et al, 20152 | Length-adjusted thrombus score at 15 ha | 27 (SD ± 24) | 25 (SD ± 16) | P = .68 |
| Mean percentage of thrombus reduction at 15 h | 55% (SD ± 27%) | 54% (SD ± 27%) | P = .91 | |
| Proportion of patients who had a thrombus load reduction ≥ 50% | 58% (n = 14) | 63% (n =15) | P > .99 | |
Abbreviations: ATTRACT, Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis; DVT, deep vein thrombosis; MT, mechanical thrombectomy; PMT, pharmacomechanical thrombectomy; SD, standard deviation.
a
A measure of thrombus size. Lower scores indicate clear vessel segments. Baseline scores were similar (P = .86) between study groups. Both groups showed statistically significant improvement (P < .01) from baseline.