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. 2023 Feb 4;13:2028. doi: 10.1038/s41598-023-29011-2

Table 2.

Comparison of selected blood parameters in classifying the severity of the main symptoms in canine babesiosis.

Symptoms and associated blood parameters ± SEM Severity class Reference values Value of statistics F P
Class 0 (normal) Class 1 (mild) Class 2 (advanced disorder)
Anemia N = 101 N = 38 N = 31
Erythrocytes (T/l) 6.75 ± 0.79 5.06 ± 0.129 3.39 ± 0.142 5.50–8.50 F2, 169 = 231.75  < 0.001
Leukocytes (G/l) 8.09 ± 0.562 7.17 ± 0.917 8.12 ± 1.015 6.0–12.0 F2, 169 = 0.40 0.673
Hemoglobin (mmol/l) 9.96 ± -0.122 7.56 ± 0.199 5.21 ± 0.220 9.30–11.8 F2, 169 = 194.04  < 0.001
Hematocrit (%) 39.51 ± 1.778 26.48 ± 2.899 15.90 ± 3.210 44.0–55.0 F2, 169 = 23.28  < 0.001
Thrombocytes (g/l) 164.40 ± 14.680 151.23 ± 23.932 28.10 ± 26.497 150.0–500.0 F2, 169 = 10.36  < 0.001
Hepatic dysfunction N = 80 N = 48 N = 33
AST (U/l) 42.50 ± 10.146 82.53 ± 13.099 140.56 ± 15.798 1.0–76.0 F2, 160 = 13.90  < 0.001
ALT (U/l) 38.10 ± 7.330 65.49 ± 9.366 124.46 ± 11.413 1.0–80.0 F2, 161 = 20.28  < 0.001
ALP (U/l) 68.89 ± 6.229 124.67 ± 8.049 249.81 ± 9.960 1.0–141.0 F2, 160 = 117.93  < 0.001
Renal dysfunction N = 106 N = 33 N = 24
Creatinine (mg/dl) 0.899 ± 0.093 1.003 ± 0.167 1.795 ± 0.195 0.396–1.49 F2, 162 = 8.62  < 0.001
Serum urea (mg/dl) 31.69 ± 5.180 70.06 ± 9.284 190.40 ± 10.887 19.9–50.0 F2, 162 = 87.02  < 0.001