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. 2023 Feb 4;9:43. doi: 10.1038/s41420-022-01294-w

Fig. 8. Scheme of NSUN2 in DOX-induced myocardial injury.

Fig. 8

NSUN2 promote the methylation modification of Nrf2 mRNA, and increase the level of Nrf2 protein, which activates the downstream antioxidant stress response and reduces the damage caused by ROS.