Table 2.
Basic characteristics in patients by state of hyponatremia.
| Dilutional Hyponatremia (n=182) | Depletional Hyponatremia (n=142) | P value | |
|---|---|---|---|
| Male | 58 (31.9) | 69 (48.6) | .003 |
| Age >70 years | 144 (79.1) | 89 (62.7) | .002 |
| Diabetes | 61 (33.5) | 39 (27.5) | .294 |
| Chronic kidney disease | 68 (37.4) | 29 (20.6) | .002 |
| Chronic obstructive pulmonary diseases | 19 (10.4) | 18 (12.7) | .651 |
| Pulse (beats/min) | 82.6 (23.3) | 88.5 (22.3) | .022 |
| Body mass index (kg/m2) | 20.6 (3.5) | 21.0 (3.8) | .332 |
| Systolic blood pressure (mmHg) | 125.1 (23.8) | 118.5 (22.1) | .012 |
| Diastolic blood pressure (mmHg) | 71.4 (13.7) | 71.5 (12.4) | .957 |
| Left ventricular ejection fractions (%) | 52 (41-62) | 49 (38-60) | .744 |
| Hemoglobin (g/dL) | 9.6 (2.0) | 13.8 (1.6) | <.001 |
| Alanine aminotransferase (U/L) | 17 (12-28) | 21 (15-36) | .005 |
| Albumin (g/L) | 34.5 (5.6) | 38.0 (4.9) | <.001 |
| Creatinine (mg/dL) | 1.59 (1.12) | 1.16 (0.68) | <.001 |
| Uric acid (mg/dL) | 8.94 (3.54) | 8.37 (3.15) | .133 |
| Potassium (mmol/L) | 4.36 (1.01) | 4.25 (0.77) | .300 |
| Triglyceride (mmol/L) | 0.92 (0.68-1.24) | 1.00 (0.74-1.34) | .186 |
| Total cholesterol (mmol/L) | 3.36 (1.07) | 4.02 (1.14) | <.001 |
| High density lipoprotein cholesterol (mmol/L) | 1.00 (0.37) | 1.13 (0.41) | .005 |
| Low density lipoprotein cholesterol (mmol/L) | 1.59 (0.65) | 2.09 (0.77) | <.001 |
| Fibrinogen (g/L) | 3.46 (1.20) | 3.58 (1.32) | .408 |
| B-type natriuretic peptide (pg/mL) | 695 (334-1902) | 593 (163-1514) | .032 |
| Angiotensin converting enzyme inhibitors | 58 (31.9) | 54 (38.0) | .299 |
| Intravenous diuretic use | 161 (88.5) | 128 (90.1) | .762 |
Data are n (%), mean (standard deviation) or median (interquartile range)