Figure 3:

Illustrative phase diagram of genome organization. We identified three phases corresponding to the conventional (blue), intermediate (yellow), and inverted (red) nuclei using the average density ratio of the outer shell over the inner sphere. Representative configurations of the three phases are shown in Figure 2b (conventional), 2a (intermediate), and 2e (inverted). The x and y axes indicate the strength of active and passive forces. The number in each bin measures the average density ratio of the outer shell over the inner sphere (a), the average volume assigned to each heterochromatin region (b), and the radius of gyration for the largest cluster formed by B compartments (c). The solid lines in parts b and c correspond to the phase boundaries shown in part a. See also Figure S9 for the corresponding results for A compartments.