TABLE 3.
Translational regulatory mechanisms of influenza virus
| Strategy | Reference(s) |
|---|---|
| Host shutoff of cellular protein synthesis | 250, 288 |
| Inhibition of cellular mRNA transport and degradation of mRNAs in the nucleus | 250 |
| Inhibition of PKR by P58IPK | 135, 249, 294–296, 447 |
| Inhibition of PKR by NS1 | 184, 312, 448 |
| Cap-dependent, selective translation of influenza virus mRNAs | 140, 142, 247, 250, 362 |
| Inhibition of cellular mRNA translation at initiation and elongation stages | 140, 247 |
| Innate ability of influenza virus mRNAs for preferential translation | 140, 142, 247 |
| Viral 5′ UTR-mediated preferential translation of influenza virus mRNAs | 361, 362 |
| Recruitment of eIF4G to the viral mRNA | 9 |
| Dephosphorylation of eIF4E | 110 |
| Temporal regulation of influenza virus protein synthesis | 102, 486, 487 |