. 2000 Jun;64(2):281–315. doi: 10.1128/mmbr.64.2.281-315.2000

TABLE 6.

Genes encoding mitochondrial carriers/transporters and genes involved directly or indirectly in oxidative stress

Gene^aProtein function^s	Protein function^e	Type of mutation	Petite production	Reference^j
MIR1^c (NE)	Mitochondrial phosphate carrier	Disruption?	rho⁻ and/or rho⁰ⁱ	333 ^k
RIM2/MRS12^b (NE)	Mitochondrial carrier family	Disruption	rho⁰^g^h	311
ATM1^b,d (NE)	Mitochondrial ABC transporter (iron homeostasis)	Disruption	rho⁻^g^h	178
GSH1^b (E)	γ-Glutamylcysteine synthetase	Point mutations	rho⁰^h	157
YFH1^b,d (NE)	Mitochondrial iron homeostasis	Disruption	rho⁻ and/or rho⁰^f^g	11
		Deletion	rho⁰^f^g^h	328
		Disruption	rho⁻ and/or rho⁰^g^h (in some genetic backgrounds)	95
SSH1^d/SSC2^b/SSQ1 (NE)	Mitochondrial Hsp70 homologue (iron homeostasis)	Point mutation	rho⁻ and/or rho⁰^g	159 ^l

to j See Table 1 footnotes.

Murakami et al. (211) reported contradictory data (see “The world of carriers and transporters”).

Schilke et al. (263) reported contradictory data (see “Oxidative stress, iron homeostasis, and mtDNA and “No compromise” and Table 13).