Table 2.
Linear regression of ED clinical features and family history of schizophrenia
| 1st-degree relatives with schizophrenia | Any relative with schizophrenia | ||||
|---|---|---|---|---|---|
| ED types | Regression coefficient (95% CI) | p value | Regression coefficient (95% CI) | p value | |
| AN | Age at first diagnosis | 0.21 (−0.60 to 1.02) | 0.62 | −0.14 (−0.44 to 0.17) | 0.37 |
| BMIa | 1.14 (0.19 to 2.10) | 0.018 | −0.26 (−0.57 to 0.04) | 0.094 | |
| EDE-Q scoresb | |||||
| Restraint | 0.02 (−0.64 to 0.68) | 0.954 | −0.32 (−0.61 to −0.03) | 0.031 | |
| Eating concern | −0.29 (−0.80 to 0.21) | 0.25 | −0.23 (−0.46 to −0.0004) | 0.049 | |
| Weight concern | −0.24 (−0.87 to 0.39) | 0.448 | −0.29 (−0.56 to −0.01) | 0.039 | |
| Shape concern | −0.26 (−0.85 to 0.32) | 0.378 | −0.37 (−0.65 to −0.10) | 0.008 | |
| Global score | −0.21 (−0.75 to 0.33) | 0.448 | −0.29 (−0.54 to −0.04) | 0.021 | |
| GAFc | −1.25 (−4.90 to 2.41) | 0.503 | −1.39 (−2.89 to 0.11) | 0.070 | |
| OED | Age at first diagnosis | −0.20 (−0.76 to 0.36) | 0.485 | −0.04 (−0.26 to 0.18) | 0.707 |
| BMIa | −0.15 (−0.96 to 0.67) | 0.720 | −0.27 (−0.65 to 0.11) | 0.168 | |
| EDE-Q scoresb | |||||
| Restraint | 0.09 (−0.39 to 0.56) | 0.720 | −0.14 (−0.34 to 0.06) | 0.163 | |
| Eating concern | −0.15 (−0.54 to 0.25) | 0.461 | −0.08 (−0.24 to 0.09) | 0.350 | |
| Weight concern | −0.09 (−0.60 to 0.42) | 0.721 | −0.07 (−0.26 to 0.11) | 0.442 | |
| Shape concern | −0.20 (−0.67 to 0.26) | 0.392 | −0.18 (−0.37 to 0.005) | 0.056 | |
| Global score | −0.10 (−0.51 to 0.31) | 0.632 | −0.11 (−0.28 to 0.06) | 0.198 | |
| GAFc | −0.39 (−3.17 to 2.40) | 0.786 | −1.00 (−2.17 to 0.17) | 0.094 | |
ED, eating disorder; CI, confidence interval; AN, anorexia nervosa; OED, other eating disorders; BMI, body mass index; GAF scores, Global Assessment of Functioning scores; EDE-Q scores, Eating Disorders Examination Questionnaire scores.
Bold font indicates statistical significance, p<0.05.
a
There were 7112 individuals with AN with BMI information, and 9667 individuals with OED with BMI information.
b
There were 3556 individuals with AN with EDEQ information, and 5515 individuals with OED with EDE-Q information.
c
There were 6656 individuals with AN with GAF score information, and 8905 individuals with OED with GAF score information.