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. 2023 Jan 29;2023:9991916. doi: 10.1155/2023/9991916

Figure 2.

Figure 2

Long noncoding RNA Gm9866 is closely related to macrophage polarization. (a) LPS (lipopolysaccharide) reduced the expression levels of long noncoding RNA Gm9866. (b) IL4 (interleukin-4) increased the expression levels of long noncoding RNA Gm9866. (c) Real-time polymerase chain reaction analysis for the transfection efficiency of long noncoding RNA Gm9866. (d, e) Real-time polymerase chain reaction analysis showed that the mRNA expression of the M2-related genes MRC2 (macrophage mannose receptor 2) and MRC1 (macrophage mannose receptor 1) significantly increased after overexpression of long noncoding RNA Gm9866. (f) NF-κB (nuclear factor-κB) is a target of long noncoding RNA Gm9866. The protein level of NF-κB (nuclear factor-κB) was significantly decreased after overexpression of long noncoding RNA Gm9866. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.