Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 28;114(2):423–435. doi: 10.1111/cas.15368

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

MMP‐21 promotes the recruitment of macrophages. (A) Representative IHC staining images of MMP‐21 and CD68 in human HCC tissues. (B) The correlation between MMP‐21 and CD68‐positive macrophages. (C) Representative IHC staining images of MMP‐21 and F4/80 in liver orthotopic xenografts from tumor‐bearing mouse. (D) Cell count of macrophages. (E, F) Transwell assays to determine macrophage recruitment. (G, H) Transwell assays to determine macrophage recruitment using culture medium from HCC cells. *p < 0.05, **p < 0.01. [Correction added on 21 September 2022, after first online publication: in Figure 3, parts E, F, G and H have been replaced with the correct images].