TABLE 21.
Transporters for which three-dimensional structural data have been reporteda
| Transporter type and TC no. | Protein | Family | Source | PDB codeb |
|---|---|---|---|---|
| 1.A. α-Type channels | ||||
| 1.A.1.1.1 | K+ channel, KcsA | VIC | Streptomyces lividans | 1BL8 |
| 1.A.9.1.1 | Acetylcholine receptor | LIC | Torpedo electric organ | 3MRA |
| 1.A.21.1.1 | Apoptosis regulator, Bcl-X(L) | Bcl-2 | Homo sapiens | 1MAZ |
| 1.A.22.1.2 | Mechanosensitive channel | MscL | Mycobacterium tuberculosis | 1MSL |
| 1.B. β-Barrel porins | ||||
| 1.B.1.1.1 | Porin (OmpC) | GBP | E. coli | 1IIV (Theo.) |
| 1.B.1.1.2 | Porin (PhoE) | GBP | E. coli | 1PHO |
| 1.B.1.1.3 | Porin (OmpF) | GBP | E. coli | 1OPF |
| 1.B.3.1.1 | Maltoporin (LamB) | SP | Salmonella typhimurium | 1MAL |
| 1.B.6.1.1 | Porin (OmpA) | OOP | E. coli | 1BXW |
| 1.B.7.1.1 | Porin (PorCa) | RPP | Rhodobacter capsulatus | 2POR |
| 1.B.14.1.4 | FhuA ferrichrome receptor | OMR | E. coli | 1BY5 |
| 1.C. Pore-forming protein and peptide toxins | ||||
| 1.C.1.1.1 | Colicin Ia | Colicin | E. coli | 1CII |
| 1.C.1.2.2 | Colicin E1 | Colicin | E. coli | 1COL |
| 1.C.2.1.1 | Cry 1Aa | ICP | Bacillus thuringiensis | 1CIY |
| 1.C.2.2.1 | Cry 3Aa | ICP | Bacillus thuringiensis | 1DLC |
| 1.C.3.1.1 | α-Hemolysin | αHL | Staphylococcus aureus | 7AHL |
| 1.C.4.1.1 | Aerolysin | Aerolysin | Aeromonas hydrophila | 1PRE |
| 1.C.18.1.1 | Melittin | CAP | Bee venom | 2MLT |
| 1.C.19.1.1 | Defensin 1 | CAP | Homo sapiens | 1DFN |
| 1.D. Non-ribosomally synthesized channels | ||||
| 1.D.1.1.1 | Gramicidin A | Gramicidin | Bacillus brevis | 1GMK |
| 3.D. Redox-driven proton pumps | ||||
| 3.D.3.2.1 | Quinol:cytochrome c reductase | QCR | Bos taurus | 1RIE |
| 3.D.4.6.1 | Cytochrome c oxidase | COX | Paracoccus denitrificans | 1ARI |
| 3.D.4.7.1 | Cytochrome c oxidase | COX | Bos taurus | 1OCC |
| 3.E. Light-driven proton pumps | ||||
| 3.E.1.1.1 | Bacteriorhodopsin | BR | Halobacterium salinarum | 1BRR |
| 3.E.2.1.1 | Reaction center | RC | Rhodobacter sphaeroides | 1PSS |
a
Three-dimensional structural data for transporters included within TC categories 2, 3A, 3B, 3C, 4, 8, and 9 are not yet available. Structures of water-soluble domains of ABC transporters (TC 3.A.1), F-type ATPases (TC 3.A.2), P-type ATPases (TC 3.A.3), several PTS permeases (TC 4.A.1–4.A.3 and 4.A.6), and the MerTP permease (TC 9.A.2) are also available. Literature citations describing the structural data summarized in this table are available by reference to our web site.
b
PDB code, code for the protein database containing the three-dimensional structure of this protein.