Table 2. Associations of levels of HDL-C and CEC with alcohol consumption using regression analysis.
| HDL-C (mg/dl) | CEC | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Bi-variable model | Multivariable model 1 | Bi-variable model | Multivariable model 1 | Multivariable model 2 | ||||||
| B (SE) | P value | B (SE)† | P value | B (SE) | P value | B (SE) † | P value | B (SE)‡ | P value | |
| All subjects | ||||||||||
| Alcohol consumption (g/day) | 0.15 (0.04) | ＜0.001 | 0.17 (0.03) | ＜0.001 | 0.02 (0.03) | 0.609 | 0.03 (0.04) | 0.396 | -0.06 (0.03) | 0.063 |
| ALDH2 ＊1/＊1 genotype | ||||||||||
| Alcohol consumption (g/day) | 0.09 (0.05) | 0.044 | 0.15 (0.04) | ＜0.001 | -0.02 (0.04) | 0.701 | 0.02 (0.04) | 0.702 | -0.06 (0.04) | 0.162 |
| ALDH2 ＊1/＊2 or ＊2/＊2 genotype | ||||||||||
| Alcohol consumption (g/day) | 0.16 (0.06) | 0.012 | 0.20 (0.06) | ＜0.001 | 0.02 (0.06) | 0.749 | 0.05 (0.06) | 0.501 | -0.07 (0.05) | 0.141 |
†Adjusted by age, BMI ≥ 25 kg/m2, LDL-C, Log-TGs, smoking status and ALDH2 genotype. ‡Adjusted by HDL-C, age, BMI ≥ 25 kg/m2, LDL-C, Log-TGs, smoking status and ALDH2 genotype.
HDL-C, high-density lipoprotein cholesterol; CEC, cholesterol efflux capacity; B, unstandardized regression coefficients; SE, standard error; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; TGs, triglycerides.