Supplemental Table 2. Associations of ALDH2 rs671 polymorphism with antioxidant or oxidative stress markers.
| Albumin (g/dL) | UA (mg/dL) | Total bilirubin (mg/dL) | Oxidized HSA (%) | |||||
|---|---|---|---|---|---|---|---|---|
| B (SE)† | P value | B (SE) † | P value | B (SE) † | P value | B (SE) † | P value | |
| All subjects | ||||||||
| ALDH2 ＊1/＊1 genotype | 0 | 0 | 0 | 0 | ||||
| ALDH2 ＊1/＊2 or ＊2/＊2 genotype | -0.04 (0.02) | 0.043 | -0.38 (0.11) | 0.001 | -0.04 (0.03) | 0.170 | 0.60 (0.34) | 0.076 |
| Subjects with no drinking habit | ||||||||
| ALDH2 ＊1/＊1 genotype | 0 | 0 | 0 | 0 | ||||
| ALDH2 ＊1/＊2 or ＊2/＊2 genotype | 0.03 (0.04) | 0.467 | -0.33 (0.22) | 0.138 | 0.01 (0.06) | 0.855 | -0.45 (0.82) | 0.587 |
| Subjects with drinking habit | ||||||||
| ALDH2 ＊1/＊1 genotype | 0 | 0 | 0 | 0 | ||||
| ALDH2 ＊1/＊2 or ＊2/＊2 genotype | -0.08 (0.03) | 0.003 | -0.23 (0.14) | 0.096 | -0.05 (0.04) | 0.241 | 0.75 (0.38) | 0.048 |
†Adjusted by age, BMI ≥ 25 kg/m2, LDL, log TG, smoking status and HDL-C.
ALDH2, aldehyde dehydrogenase 2; UA, uric acid; HSA, human serum albumin; B, unstandardized regression coefficients; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; TGs, triglycerides; HDL-C, high-density lipoprotein cholesterol.