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. 2022 Mar 4;30(1):23–38. doi: 10.5551/jat.63277

Supplemental Table 3. Associations of levels of CEC and HDL-C with drinking habit categories among normal weight or overweight subjects.

HDL-C (mg/dl) CEC
Bi-variable model Multivariable model Bi-variable model Multivariable model 1 Multivariable model 2
B (SE) P value B (SE) P value B (SE) P value B (SE) P value B (SE) P value
Subjects with normal weight
No drinking habit 0 0 0.003§ 0 0 0 0.034§
0.1-22.9 g/day 2.51 (1.89) 0.186 1.43 (1.76) 0.415 2.15 (1.73) 0.215 0.94 (1.78) 0.600 0.21 (1.55) 0.893
23-45.9 g/day 3.35 (2.37) 0.156 3.70 (2.33) 0.113 -0.99 (2.17) 0.648 -0.65 (2.36) 0.784 -2.53 (2.05) 0.220
>46 g/day 6.60 (2.97) 0.027 8.97 (2.86) <0.001 -1.35 (2.72) 0.619 -0.83 (2.90) 0.775 -5.39 (2.55) 0.035||
Overweight subjects
No drinking habit 0 0 0.003§ 0 0 0 0.545§
0.1-22.9 g/day 6.84 (2.91) 0.020 4.87 (2.94) 0.101 2.83 (2.97) 0.342 0.92 (3.15) 0.769 -2.01 (2.64) 0.449
23-45.9 g/day 9.77 (3.45) 0.005 7.64 (3.44) 0.028|| 6.96 (3.52) 0.050 5.17 (3.68) 0.163 0.57 (3.11) 0.854
>46 g/day 12.48 (4.26) 0.004 11.42 (4.17) 0.007 2.84 (4.34) 0.515 2.90 (4.46) 0.518 -3.98 (3.81) 0.298

Adjusted by age, BMI ≥ 25 kg/m2, LDL-C, Log-TGs, smoking status and ALDH2 genotype.

Adjusted by HDL-C, age, BMI ≥ 25 kg/m2, LDL-C, Log-TGs, smoking status and ALDH2 genotype.

§P values for trend.

|| Significance disappeared after Bonferroni’s correction.

HDL-C, high-density lipoprotein cholesterol; CEC, cholesterol efflux capacity; B, unstandardized regression coefficients; SE, standard error; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; TGs, triglycerides; ALDH2, aldehyde dehydrogenase 2.