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. 2022 Oct 17;33(1):15–27. doi: 10.4014/jmb.2207.07032

Fig. 3. Proposed BP exopolysaccharide biosynthesis regulation mechanism via c-di-GMP and QS signaling.

Fig. 3

Signaling molecules, e.g. c-di-GMP, and QS molecules, e.g., RpoS and AHLs, regulate the development of the EPS components, particularly exopolysaccharides. c-di-GMP is reported to improve the binding between the regulatory protein and the promoter region of the becA-R gene cluster thereby triggering gene expression of the cluster to produce the enzymes that facilitate the synthesis of exopolysaccharides in the EPS.