FIG. 5.
Domains and interaction regions of the global coactivator HATs p300/CBP. Labeled below the polypeptide diagram are several domains and sequence motifs, including a bromodomain, the HAT domain, and ZZ and TAZ putative zinc fingers (190). Above are indicated some of the proteins demonstrated to interact with p300/CBP at certain regions. PCAF has been shown to interact with two regions of p300/CBP (130).