TABLE 3.

Grain size and roughness from AFM image analysis.

Group (M)	Subchondral bone		Cartilage
	Grain size (nm)	Roughness (nm)	Grain size (nm)	Roughness (nm)
1	41.588 (37.583, 48.050)	9.360 (6.908, 12.455)	79.946 (73.008, 82.798)	3.931 (2.439, 4.451)
3	37.712 (33.822, 39.776)	8.385 (6.548, 10.545)	58.256 (45.029, 61.277)	4.034 (4.019, 4.980)
6	42.151 (39.339, 44.269)	9.815 (7.908, 13.300)	43.197 a (32.255, 52.005)	4.858 a (4.154, 5.394)
9	47.370 (42.293, 58.290)	8.620 (6.485, 9.248)	45.536 a (33.380, 48.348)	5.510 a (5.454, 6.157)

Values are presented as median (IQR).

^a Significantly different from 1 M; p < 0.05.