Table 3.

Logistic regression analysis, endpoints hrHPV positivity, CIN 2+ and CIN 3+ (with imputation), women aged 35+ years who have previously been screened (N = 720,976).

	Unadjusted model	Adjusted models
	Model 1	Model 2a	Model 3b	Model 4c
	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
hrHPV positivity
Clinician-collected	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
Self-sampling	0.73 (0.70–0.76)	0.73 (0.70–0.77)	0.73 (0.70–0.76)	0.66 (0.63–0.69)
CIN 2+
Clinician-collected	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
Self-sampling	0.78 (0.69–0.88)	0.78 (0.69–0.88)	0.78 (0.69–0.88)	0.73 (0.65–0.83)
CIN 3+
Clinician-collected	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
Self-sampling	0.87 (0.75–1.02)	0.88 (0.75–1.03)	0.88 (0.75–1.03)	0.83 (0.71–0.97)

Note: All cases with missing values for household income and/or screening region (0.8% of total cohort) are excluded from the analyses presented in this table. Ten rounds of imputation were used to replace missing CIN2+/CIN3+ endpoints for women with a hrHPV-positive self-sampling and no cytology result. Pooled ORs are presented for these endpoints. Pooled ORs with 95% CI not including 1.00 are shown in bold.

^aAdjusted for age.

^bAdjusted for age and screening region.

^cAdjusted for age, screening region, and sociodemographic characteristics.