Fig. 4.

Effects of Fr. (c) on the production of LPS-Induced pro-Inflammatory cytokines in RAW264.7 cells. The expression level of TNF-α (A), PGE2 (B), IL-1β (C) and IL-6 (D) were measured as described in the materials and method. The mRNA expression level of IL-6 (E), IL-1β (F), TNF-α (G) were measured by RT-qPCR in the RAW264.7 cells. Data shown represent the mean ± SD (n = 3). ###p < 0.001 when compared with control versus LPS; ***p < 0.001, **p < 0.01, *p < 0.05 as compared to the group treated with LPS alone.