Fig. 7.

Effects of Fr. (c) on NF-κB protein expression in LPS-stimulated RAW264.7 cells. RAW264.7 macrophages were pretreated with various concentrations of Fr. (c) for 2 h, then was co-treated with LPS (1 μg/mL) for 18 h. The expression levels of IκBα, p-IκBα, P65, and p-P65 in the nucleus were detected using Western blot analysis. Data shown represent the mean ± SD (n = 3). ###p < 0.001 when compared with control versus LPS; ***p < 0.001, **p < 0.01, *p < 0.05 as compared to the group treated with LPS alone.