TABLE 3.
Performance of each symptom intensity scale, spirometric indices and exhaled nitric oxide fraction (FENO) to diagnose asthma in the training cohort (n=166)
| Threshold | AUC (95% CI) | Sensitivity (%) | Specificity (%) | p-value AUC | |
| Wheezing intensity score | 0.5 | 0.67 (0.59–0.76) | 78 (69–86) | 54 (41–67) | 0.0002 |
| Dyspnoea intensity score | 2.5 | 0.56 (0.46–0.64) | 38 (29–48) | 69 (56–80) | 0.2485 |
| Cough intensity score | 0.5 | 0.53 (0.44–0.62) | 88 (80–93) | 20 (11–32) | 0.5410 |
| Airway secretion intensity score | 0.5 | 0.56 (0.47–0.65) | 75 (66–83) | 34 (23–48) | 0.1847 |
| Chest tightness intensity score | 2.5 | 0.51 (0.42–0.60) | 28 (19–37) | 77 (65–87) | 0.8762 |
| FEV1 (% pred) | 96 | 0.68 (0.60–0.77) | 71 (62–80) | 59 (46–71) | <0.0001 |
| FEV1/FVC (%) | 78 | 0.69 (0.61–0.77) | 54 (44–64) | 79 (66–88) | <0.0001 |
| FENO (ppb) | 33 | 0.56 (0.47–0.66) | 32 (23–43) | 83 (71–92) | 0.1839 |
FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. Bold indicates statistical significance.