Table 2:
Linear regression of change in PHQ-9 score associated with covariables in fully adjusted Model 4.
| Coefficient | Lower 95% CI | Upper 95% CI | P | |
|---|---|---|---|---|
| CFS score | 0.768 | 0.397 | 1.14 | <.001 |
| Age | −0.093 | −0.137 | −0.050 | <.001 |
| Ethnicity | ||||
| White | REFERENCE | |||
| South Asian | −1.54 | −2.74 | −0.344 | .012 |
| Black | −0.689 | −1.96 | 0.578 | .286 |
| Other | −0.007 | −2.83 | 2.81 | .996 |
| Gender | ||||
| Male | REFERENCE | |||
| Female | 0.527 | −0.366 | 1.42 | .246 |
| IMD quintile | ||||
| 1 | REFERENCE | |||
| 2 | −0.164 | −1.37 | 1.05 | .790 |
| 3 | −0.083 | −1.31 | 1.14 | .894 |
| 4 | −0.611 | −2.27 | 1.05 | .471 |
| 5 | −0.424 | −2.18 | 1.34 | .636 |
| Unknown | 0.062 | −1.88 | 2.00 | .950 |
| Education level | ||||
| High school | REFERENCE | |||
| College/6th form | −0.919 | −2.05 | 0.209 | .110 |
| University | −1.91 | −3.39 | −0.422 | .012 |
| Prior admissions | −0.008 | −0.188 | 0.172 | .931 |
| Charlson Indexa | −0.079 | −0.350 | 0.193 | .570 |
| Cognitive impairment | ||||
| No | REFERENCE | |||
| Yes | −0.366 | −1.49 | 0.753 | .521 |
| Antidepressant use | ||||
| No | REFERENCE | |||
| Yes | 3.69 | 2.29 | 5.09 | <.001 |
| Number medications | 0.075 | −0.056 | 0.206 | .260 |
| HD vintage | −0.001 | −0.010 | 0.007 | .778 |
| Self-rated pain | ||||
| None | REFERENCE | |||
| Moderate | 1.63 | 0.664 | 2.60 | .001 |
| Extreme | 2.61 | 0.867 | 4.36 | .003 |
| Self-rated health change | ||||
| Better/The same | REFERENCE | |||
| Worse | 1.73 | 0.808 | 2.65 | <.001 |
| Self-rated health/100 | −0.056 | −0.078 | −0.034 | <.001 |
| Constant | 10.6 | 7.19 | 14.1 | <.001 |
Coefficients derived from multiple linear regression. Bold text indicates significant at P < .05 level.
aCKD omitted from Charlson Index.