Table 3:

Linear regression of change in CFS score associated with covariables in fully adjusted Model 4.

	Coefficient	Lower 95% CI	Upper 95% CI	P
PHQ-9 score	0.046	0.027	0.064	<.001
Age	−0.008	−0.017	0.001	.083
Gender
Male	REFERENCE
Female	0.226	0.040	0.412	.017
Ethnicity
White	REFERENCE
South Asian	0.214	−0.037	0.466	.095
Black	−0.012	−0.278	0.254	.929
Other	0.257	−0.331	0.844	.391
Education level
High school	REFERENCE
College/6th form	0.008	−0.224	0.240	.945
University	−0.152	−0.468	0.163	.344
IMD quintile
1	REFERENCE
2	0.104	−0.147	0.354	.416
3	0.015	−0.238	0.269	.905
4	−0.301	−0.647	0.045	.088
5	0.007	−0.362	0.376	.969
Unknown	0.156	−0.240	0.551	.439
Social support
No	REFERENCE
Yes	−0.698	−1.07	−0.332	<.001
Charlson Indexa	0.094	0.040	0.147	.001
Cognitive Impairment
No	REFERENCE
Yes	0.030	−0.201	0.261	.798
Smoking status
Current	REFERENCE
Ex	0.277	−0.013	0.566	.061
Never	0.172	−0.100	0.444	.214
Self-rated health change
Better/The same	REFERENCE
Worse	0.075	−0.117	0.267	.441
Self-rated health/100	−0.006	−0.011	−0.002	.006
Walking aid use
No	REFERENCE
Yes	0.532	0.307	0.758	<.001
Physical Activity Index
Inactive	REFERENCE
Moderately inactive	−0.384	−0.732	−0.035	.031
Moderately active	−1.07	−1.49	−0.641	<.001
Active	−1.86	−2.30	−1.42	<.001
Slow walking speed
No	REFERENCE
Yes	0.712	0.482	0.941	<.001
Low grip strength
No	REFERENCE
Yes	0.082	−0.119	0.283	.424
Constant	3.88	3.20	4.55	<.001

Coefficients derived from multiple linear regression. Bold text indicates significant at P < 0.05 level.

^aCKD omitted from Charlson Index.