Table 6.
Treatment-emergent interstitial lung disease events by menopausal status.
| Premenopausal | Abemaciclib + ET, n = 1222, n (%) | ET alone, n = 1209, n (%) | ||||
|---|---|---|---|---|---|---|
| Any grade | Grade 3 | Grade 4 | Any grade | Grade 3 | Grade 4 | |
| Interstitial lung diseasea | 44 (3.6) | 3 (0.2) | 0 | 19 (1.6) | 0 | 0 |
| Postmenopausal | Abemaciclib + ET, n = 1565, n (%) | ET alone, n = 1591, n (%) | ||||
| Any grade | Grade 3 | Grade 4 | Any grade | Grade 3 | Grade 4 | |
| Interstitial lung diseasea | 45 (2.9) | 7 (0.4) | 0 | 18 (1.1) | 1 (0.1) | 0 |
a
Identified by interstitial lung disease events SMQ.
ET, endocrine therapy.