Prediction of optical rotations of l-amino acids in their protonated forms. Note: cysteine: no σ_p on –CH₂SH, but it should be <0 (–CH₂OH); lysine: no σ_p on –(CH₂)₄NH₃⁺, –(CH₂)₃N⁺(Me)₃ (−0.01) was used instead; methionine: no σ_p on –CH₂CH₂SCH₃. It will be close to –CH₂CH₂CH₃ (−0.15); tryptophan: no σ_p on the –CH₂-ring. It will be close to –CH₂CH CH₂ (−0.14); glutamine: no σ_p for CH₂CH₂CONH₂. It will be close to CH₂CH₂COOH (−0.07); histidine: no σ_p on –CH₂-ring. It will be close to –CH₂CH CH₂ (−0.14).

l-Alanine (+13)	l-Arginine (+21.6)	l-Asparagine (+34)	l-Aspartic acid (+24.4)	l-Cysteine (+7.9)
l-Glutamine (+6.5)	l-Glutamic acid (+31.5)	Glycine (not chiral)	l-Histidine (+13)	l-Isoleucine (+51.8) two chiral centers
l-Leucine (+14.9)	l-Lysine (+20.5)	l-Methionine (22.8)	l-Phenylalanine (−7.4)	l-Proline (−69)
l-Serine (+15.9)	l-Threonine (−17.9)	l-Tryptophan (+13)	l-Tyrosine (−10.1)	l-Valine (+26.9)
	Two chiral centers