Skip to main content
[Preprint]. 2024 Mar 2:2023.01.24.523981. Originally published 2023 Jan 25. [Version 2] doi: 10.1101/2023.01.24.523981

Fig. 4. Largely normal non-allodynia sensory domains of foot (glabrous) skin from mice lacking skin keratinocyte-derived SIRT1.

Fig. 4.

(A) Adhesive removal assay, (B) Light touch assay, (C) Hargreaves assay, (D) Hot plate assay, (E) Acetone evaporation assay, and (F) Pinprick assay. Note that in all 3 groups the latency to detection of the adhesive was increased after HFD treatment, but there was no significant difference between the controls and SIRT1 KO mice. Error bars indicate SEM. Statistics were performed by two-way ANOVA: **** p < 0.0001, ** p < 0.01, * p < 0.05, ns = non-significant.