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[Preprint]. 2023 Jan 25:2023.01.25.525538. [Version 1] doi: 10.1101/2023.01.25.525538

Figure 2. DMPA and N-IVR similarly dampen HPO axis function.

Figure 2.

A) Timeline for collecting genital biopsy tissue and blood from study animals. B) Left two panels display mean serum levels of MPA and ENG (before and after initiating DMPA or N-IVR ); right two panels show comparable mean serum levels of endogenous P4 and E2 in DMPA- and N-IVR-treated RM. DMPA, depot-medroxyprogesterone acetate; E2, estrogen; ENG, etonogestrel; N-IVR, re-sized NuvaRing®; MPA, medroxyprogesterone acetate; P4, progesterone; RM, rhesus macaques.