. Author manuscript; available in PMC: 2023 Feb 6.

Published in final edited form as: J Affect Disord. 2015 Dec 30;192:212–218. doi: 10.1016/j.jad.2015.12.036

Table 2.

Association between changes in clinical variables and 14-item CHRT over 6-months.

Variable	Covariance of slopes [95% CI]	Correlation coefficient	P-value
CGI-BP
Overall severity	0.35 [0.21, 0.49]	0.54	<0.0001
Depression	0.44 [0.28, 0.60]	0.58	<0.0001
Mania	0.10 [−0.03, 0.23]	0.13	0.14
BISS
Total	6.87 [4.56, 9.19]	0.63	<0.0001
Depression	3.15 [2.19, 4.12]	0.73	<0.0001
Mania	0.02 [−0.59, 0.62]	0.00	0.95
Anxiety	2.59 [1.66, 3.52]	0.56	<0.0001
Irritability	2.41 [1.43, 3.40]	0.53	<0.0001
Psychosis	0.47 [0.06, 0.88]	0.20	0.02

Abbreviations: BISS: Bipolar Inventory of Symptoms Scale, CGI-BP: Clinical Global Impressions-Bipolar Version, CHRT: Concise Health Risk Tracking.

Note: Numbers in table are based on mixed effects regression models, which estimated the covariance (and correlation) between patient-specific slopes of each outcome.