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[Preprint]. 2023 Jan 28:2023.01.27.525916. [Version 1] doi: 10.1101/2023.01.27.525916

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Figure 4. — Markers discovery on 10X Multiome PBMC dataset. (A) Heatmap showing the gene-peak correlations in pseudo-bulk data of B cell clusters. Each row is a pseudo-bulk, each column is a gene-peak pair, and color indicates the correlation level. (B) Heatmap showing the gene-peak correlations in pseudo-bulk data of CD4+ T cell clusters. (C) Differentially correlated peaks in B cell clusters were enriched in PU-box binding motif. Genes linked with the peaks were extracted for Gene Ontology enrichment analysis to discover the functional changes. (D) Differentially correlated peaks in CD4+ T cell clusters were enriched in the RUNX1 binding motif. Genes linked with the peaks were extracted for Gene Ontology enrichment analysis to discover the functional changes.