Figure 4.
A126T, R130Q, and G132D in the P loop.
(A) The conformations of P loop and WPD loop for A126T, R130Q, and G132D. Key residues are marked, and the mutated residues are marked with yellow background. (B) Violin plots representing the atomic pair distance between Cα of His93 in the WPD loop and Cα of Arg130 (Gln130 for R130Q) in the P loop for A126T, G132D, and wild-type PTEN.
