Figure 3. KLC1 makes extensive contacts with KIF5C within the inhibited state.
(A) Overview of KIF5C-KLC1 domain diagram. (B) Size exclusion chromatography profile of KIF5C-KLC1. (C) Negative staining EM analysis of Kif5C-KLC1 in two states. (D) Class averages of KIF5C-KLC1 in compact conformation. (E) End to end length measurements of KIF5C-KLC1 in two states (N=100). (F) Crosslinked lysine pairs in KIF5C-KLC1 were mapped onto the domain diagram.
