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[Preprint]. 2023 Jan 27:rs.3.rs-2516002. [Version 1] doi: 10.21203/rs.3.rs-2516002/v1

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Representative in vitro autoradiography of rat (upper panel) and mouse (lower panel) brains. A. Autoradiograms after incubation with (R)-[¹⁸F]OF-NB1 only (baseline) or in combination with GluN2B antagonist, CP101,606 (10 μM). Selectivity over sigma2 receptors was assessed by blockade studies with FA10 (10 μM). B. Autoradiograms after incubation with (S)-[¹⁸F]OF-NB1 alone or in combination with GluN2B antagonist, CP101,606 (10 μM). FA10 (10 μM) was used to assess selectivity over sigma2 receptors.