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[Preprint]. 2023 Jan 27:rs.3.rs-2516002. [Version 1] doi: 10.21203/rs.3.rs-2516002/v1

Figure 2.

Figure 2

Quantification of autoradiographic data from rat brain sections. A. Distribution of (R)-[18F]OF-NB1 throughout distinct brain regions. GluN2B subunit-specificity was derived from the extent of signal reduction from baseline to CP (CP101,606) blockade. Selectivity over sigma2 receptors was assessed by the extent of signal reduction from baseline to FA10 blockade. B. Distribution of (S)-[18F]OF-NB1 throughout distinct brain regions. GluN2B subunit-specificity was derived from the extent of signal reduction from baseline to CP (CP101,606) blockade. Selectivity over sigma2 receptors was assessed by the extent of signal reduction from baseline to FA10 blockade.