Table 3.
Results of the subgroup analyses by CPR in the weighted cohort
| With CPR | Without CPR | |||||||
|---|---|---|---|---|---|---|---|---|
| Thrombolysis | Control | Risk differences | Thrombolysis | Control | Risk differences | |||
| Outcomes | (n = 263) | (n = 473) | (95% CI) | P-value | (n = 170) | (n = 314) | (95% CI) | P-value |
| Primary outcome | ||||||||
| In-hospital mortality, n (%) | 172 (66) | 309 (65) | 0.3 (− 7.1 to 7.8) | 0.93 | 67 (39) | 150 (48) | − 8.5 (− 19.0 to 2.0) | 0.11 |
| Secondary outcomes | ||||||||
| Favorable neurological outcomes, n (%) | 77 (29) | 131 (28) | 1.6 (− 5.5 to 8.7) | 0.66 | 93 (55) | 146 (47) | 7.9 (− 2.5 to 18.4) | 0.14 |
| Length of hospital stay, days, mean (SD) | 24 (43) | 21 (33) | 2.4 (− 3.7 to 8.4) | 0.45 | 33 (85) | 27 (31) | 6.3 (− 5.2 to 17.9) | 0.28 |
| Length of VA-ECMO, days, mean (SD) | 3 (3) | 3 (4) | − 0.3 (− 0.8 to 0.3) | 0.32 | 3 (3) | 4 (4) | − 0.3 (− 1.0 to 0.4) | 0.43 |
| Total hospitalization cost, × 103 dollars, mean (SD) | 28 (23) | 26 (21) | 2.1 (− 1.5 to 5.7) | 0.25 | 33 (29) | 29 (21) | 4.2 (− 1.2 to 9.5) | 0.13 |
| Major bleeding in a critical area or organ, n (%) | 11 (4) | 10 (2) | 2.0 (− 1.3 to 5.3) | 0.24 | 12 (7) | 11 (4) | 3.6 (− 1.9 to 9.2) | 0.20 |
| Intracranial bleeding, n (%) | 4 (1) | 3 (1) | 0.9 (− 1.1 to 2.9) | 0.37 | 6 (4) | 6 (2) | 1.9 (− 3.0 to 6.9) | 0.45 |
| Blood transfusions, ml, mean (SD) | ||||||||
| Red blood cells | 2710 (2450) | 2628 (2882) | 81 (− 373 to 536) | 0.73 | 3144 (3172) | 2649 (2682) | 495 (− 158 to 1148) | 0.14 |
| Fresh-frozen plasma | 1361 (1611) | 1463 (2161) | − 102 (− 420 to 216) | 0.53 | 1831 (3280) | 1329 (1776) | 502 (− 180 to 1183) | 0.15 |
| Platelet concentrate | 236 (421) | 271 (503) | − 35 (− 109 to 38) | 0.34 | 327 (777) | 337 (619) | − 9.4 (− 179 to 160) | 0.91 |
CI confidence interval, CPR cardiopulmonary resuscitation, SD standard deviation, VA-ECMO venoarterial extracorporeal membrane oxygenation