TABLE 5.
MW (g/mol) | 306.271 (PUBCHEM) |
---|---|
Ki (mg/L) | |
4’-OH-S | 8.88 (Brown et al., 2006; Damle et al., 2011) |
6-OH-S | 6.74 (Brown et al., 2006) |
7-OH-S | 6.74 (Brown et al., 2006) |
8-OH-S | 0.64 (Damle et al., 2011) |
10-OH-S | 19.3 (Brown et al., 2006; Damle et al., 2011) |
4’-OH-R | 8.88 (Brown et al., 2006; Damle et al., 2011) |
6-OH-R | 30.63 (Kunze et al., 1996) |
7-OH-R | 12.67 |
8-OH-R | 0.64 (Brown et al., 2006) |
10-OH-R | 19.3 (Brown et al., 2006; Damle et al., 2011) |
Fluconazole effects on CLR (multiplication factor) | |
S-warfarin | 0.847 (Cheng et al., 2022a) |
R-warfarin | 0.752 (Cheng et al., 2022a) |
MW, molecular weight.