TABLE 6.

Rifampin induction parameters

MW (g/mol)	822.94 (PUBCHEM)
indmax
4’-OH-S	8.4 (Krishna Machavaram, 2017; Yamazaki et al., 2019)
6-OH-S	3.6 (Krishna Machavaram, 2017)
7-OH-S	3.6 (Krishna Machavaram, 2017)
8-OH-S	5.5 (Yamazaki et al., 2019)
10-OH-S	16.0 (Yamazaki et al., 2019)
4’-OH-R	8.4 (Krishna Machavaram, 2017; Yamazaki et al., 2019)
6-OH-R	3.8 (Pelletier et al., 2013)
7-OH-R	7.8 (Pelletier et al., 2013; Krishna Machavaram, 2017; Yamazaki et al., 2019)
8-OH-R	5.5 (Yamazaki et al., 2019)
10-OH-R	16.0 (Yamazaki et al., 2019)
indC50 (mg/L)
4’-OH-S	0.239 (Krishna Machavaram, 2017; Yamazaki et al., 2019)
6-OH-S	1.234 (Krishna Machavaram, 2017)
7-OH-S	1.234 (Krishna Machavaram, 2017)
8-OH-S	0.370 (Yamazaki et al., 2019)
10-OH-S	0.263 (Yamazaki et al., 2019)
4’-OH-R	0.239 (Krishna Machavaram, 2017; Yamazaki et al., 2019)
6-OH-R	0.181 (Pelletier et al., 2013)
7-OH-R	0.214 (Pelletier et al., 2013; Krishna Machavaram, 2017; Yamazaki et al., 2019)
8-OH-R	0.370 (Yamazaki et al., 2019)
10-OH-R	0.263 (Yamazaki et al., 2019)
Rifampin effects on CLR (multiplication factor)
S-warfarin	1.30 (Cheng et al., 2022a)
R-warfarin	1.43 (Cheng et al., 2022a)

indC₅₀, concentration of rifampin producing 50% of maximum induction of a particular metabolic pathway; MW, molecular weight.