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Activation t-value for low demand semantic judgments (left) and for high demand judgments (right) in younger (ages 20–39, n = 90), middle-aged (ages 40–59, n = 127), and older adults (ages 60–89, n = 244). Activation in lateral prefrontal cortex was highly left-lateralized in younger adults but showed increasing bilaterality in older age groups and with higher task demand.
