Table 2.

Univariate activations for primary prefrontal regions of interest by age.

	Younger Adults (n = 90)	Middle-Aged (n = 127)	Older Adults (n = 244)
Region	Mean (SD)
Low Demand Condition
L PFC (VLPFC/DLPFC)	.14 (.23)***	.13 (.23)***	.23 (.24)***
R PFC (VLPFC/DLPFC)	−.04 (.20)	−.002 (.22)	.09 (.22)***
L VLPFC	.29 (.27)***	.26 (.28)***	.35 (.27)***
R VLPFC	.002 (.24)	.01 (.26)	.10 (.27)***
L DLPFC	.03 (.23)	.03 (.23)	.13 (.23)***
R DLPFC	−.06 (.21)**	−.02 (.22)	.08 (.22)***
High Demand Condition
L PFC (VLPFC/DLPFC)	.40 (.28)***	.38 (.26)***	.41 (.26)***
R PFC (VLPFC/DLPFC)	.12 (.22)***	.13 (.24)***	.17 (.24)***
L VLPFC	.60 (.34)***	.55 (.30)***	.58 (.31)***
R VLPFC	.14 (.26)***	.14 (.27)***	.17 (.29)***
L DLPFC	.26 (.27)***	.26 (.26)***	.28 (.26)***
R DLPFC	.10 (.23)***	.12 (.25)***	.16 (.25)***

Note. Raw beta means (task – fixation) for each age group are presented for each primary prefrontal region and for both semantic judgment conditions (low and high demand). Abbreviations: DLPFC, dorsolateral prefrontal cortex; VLPFC, ventrolateral prefrontal cortex. Two-tailed p-values:

^*p < .05,

^**p < .01,

^***p < .001.