The synthesis of methoxy-, phenyl- and bromo-substituted indigos.
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|---|---|---|---|---|---|---|
| Entry | R1 | R2 | Time | Yield | ||
| 1 | OMe | H | 8a | 16 h | 1a | 58% |
| 2 | OMe | OMe | 8b | 20 h | 1b | 22% |
| 3 | H | OMe | 8c | 20 h | 1c | 30% |
| 4 | Ph | H | 8d | 20 h | 1d | 36% |
| 5 | H | Ph | 8e | 20 h | 1e | 28% |
| 6 | Br | H | 8f | 16 h | 1f | 35% |
| 7 | H | Br | 8g | 20 h | 1g | 32% |