Table 2.
Association of Ln HOMA-IR with Ln OSI
| Variables | Crude Model | Adjusted Model Ia | Adjusted Model IIb | |||
|---|---|---|---|---|---|---|
| Ln HOMA-IR | β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value |
| Continuous | −0.18 (−0.21, −0.16) | <0.0001 | −0.09 (−0.12, −0.07) | <0.0001 | −0.12 (−0.15, −0.09) | <0.0001 |
| Categories | ||||||
| Quartile 1 | 0 (reference) | 0 (reference) | 0 (reference) | |||
| Quartile 2 | −0.00 (−0.05, 0.04) | 0.8995 | −0.00 (−0.04, 0.04) | 0.9460 | −0.02 (−0.06, 0.02) | 0.4078 |
| Quartile 3 | −0.10 (−0.15, −0.06) | <0.0001 | −0.04 (−0.08, −0.00) | 0.0358 | −0.07 (−0.11, −0.03) | 0.0007 |
| Quartile 4 | −0.27 (−0.31, −0.22) | <0.0001 | −0.14 (−0.19, −0.10) | <0.0001 | −0.18 (−0.22, −0.13) | <0.0001 |
| P for trend | < 0.001 | < 0.001 | < 0.001 | |||
Notes: aAdjusted: age, BMI, AMH, AFC, initial Gn dose. bAdjusted: age, BMI, AMH, AFC, initial Gn dose, basal FSH, PCOS, COH protocol, infertility type.
Abbreviations: HOMA-IR, homeostatic model assessment of insulin resistance; Ln, log e transformation; β, regression coefficient; CI, confidence interval.