Table 5.
Changes observed via ForenSeq sequencing of n = 369 father-son pairs.
| Locus | Father Alleles by Length and Sequence | Son Alleles by Length and Sequence (Mutation Bolded) | Mutation | ||
|---|---|---|---|---|---|
| DYS19 | 17 | [TCTA]14 CCTA [TCTA]3 |
18 | [TCTA]15 CCTA [TCTA]3 |
+ 1 |
|
|
|
|
|
|
|
| DYS385 a/b | 11,15 | [TTTC]11 [CCTT]6, [TTTC]15 [CCTT]6 |
12,15 | [TTTC]12 [CCTT]6, [TTTC]15 [CCTT]6 |
+1 |
|
|
|
|
|
|
|
| DYS389Ia | 14 | [TAGA]11 [CAGA]3 |
13 | [TAGA]10 [CAGA]3 |
−1 |
| 15 | [TAGA]12 [CAGA]3 |
14 | [TAGA]11 [CAGA]3 |
−1 | |
| 14 | [TAGA]11 [CAGA]3 |
15 | [TAGA]12 [CAGA]3 |
+1 | |
| 13 | [TAGA]10 [CAGA]3 |
14 | [TAGA]11 [CAGA]3 |
+1 | |
|
|
|
|
|
|
|
| DYS389II | 30 | [TAGA]9 [CAGA]3 N48 [TAGA]13 [CAGA]5 |
31 | [TAGA]9 [CAGA]3 N48 [TAGA]14 [CAGA]5 |
+1 |
|
|
|
|
|
|
|
| DYS390 | 24 | [TAGA]4 CAGA [TAGA]11 [CAGA]8 |
23 | [TAGA]4 CAGA [TAGA]10 [CAGA]8 |
−1 |
|
|
|
|
|
|
|
| DYS439 | 12, (13) | [GATA]12, ([GATA]13) | 12 | [GATA]12 | 0b |
| 13 | [GATA]13 | 12 | [GATA]12 | −1 | |
| 13 | [GATA]13 | 12 | [GATA]12 | −1 | |
| 13 | [GATA]13 | 12 | [GATA]12 | −1 | |
| 12 | [GATA]12 | 13 | [GATA]13 | +1 | |
| 14 | [GATA]14 | 15 | [GATA]15 | +1 | |
|
|
|
|
|
|
|
| DYS456 | 15 | [AGAT]15 | 16 | [AGAT]16 | +1 |
|
|
|
|
|
|
|
| DYS460 | 11 | [CTAT]11 | 10 | [CTAT]10 | −1 |
| 11 | [CTAT]11 | 10 | [CTAT]10 | −1 | |
| 12 | [CTAT]12 | 11 | [CTAT]11 | −1 | |
| 10 | [CTAT]10 | 11 | [CTAT]11 | +1 | |
|
|
|
|
|
|
|
| DYS481 | 24 | [CTT]24 | 25 | [CTT]25 | +1 |
| 25 | [CTT]25 | 26 | [CTT]26 | +1 | |
|
|
|
|
|
|
|
| DYS505 | 13, (14) | [TCCT]13, ([TCCT]14) | 13 | [TCCT]13 | 0b |
| 12 | [TCCT]12 | 11 | [TCCT]11 | −1 | |
| 14 | [TCCT]14 | 13 | [TCCT]13 | −1 | |
| 14 | [TCCT]14 | 13 | [TCCT]13 | −1 | |
|
|
|
|
|
|
|
| DYS522 | 12 | [ATAG]12 | 11 | [ATAG]11 | −1 |
|
|
|
|
|
|
|
| DYS549 | 13 | [GATA]13 | 12 | [GATA]12 | −1 |
| 13 | [GATA]13 | 14 | [GATA]14 | +1 | |
|
|
|
|
|
|
|
| DYS570c | 17 | [TTTC]17 | 16 | [TTTC]16 | −1 |
| 21 | [TTTC]21 | 20 | [TTTC]20 | −1 | |
| 17 | [TTTC]17 | 18 | [TTTC]18 | +1 | |
| 17 | [TTTC]17 | 18 | [TTTC]18 | +1 | |
| 17 | [TTTC]17 | 18 | [TTTC]18 | +1 | |
|
|
|
|
|
|
|
| DYS576c | 19 | [AAAG]19 | 18 | [AAAG]18 | −1 |
| 21 | [AAAG]21 | 20 | [AAAG]20 | −1 | |
| 16 | [AAAG]16 | 17 | [AAAG]17 | +1 | |
| 19 | [AAAG]19 | 20 | [AAAG]20 | +1 | |
|
|
|
|
|
|
|
| DYS612c | 34 | [CCT]5 CTT [TCT]4 CCT [TCT]23 |
32 | [CCT]5 CTT [TCT]4 CCT [TCT]21 |
−2 |
| 35 | [CCT]5 CTT [TCT]4 CCT [TCT]24 |
34 | [CCT]5 CTT [TCT]4 CCT [TCT]23 |
−1 | |
| 37 | [CCT]5 CTT [TCT]4 CCT [TCT]26 |
36 | [CCT]5 CTT [TCT]4 CCT [TCT]25 |
−1 | |
| 39 | [CCT]5 CTT [TCT]4 CCT [TCT]28 |
40 | [CCT]5 CTT [TCT]4 CCT [TCT]29 |
−1 | |
| 37 | [CCT]5 CTT [TCT]4 CCT [TCT]26 |
38 | [CCT]5 CTT [TCT]4 CCT [TCT]27 |
+1 | |
| 38 | [CCT]5 CTT [TCT]4 CCT [TCT]27 |
39 | [CCT]5 CTT [TCT]4 CCT [TCT]28 |
+1 | |
| 38 | [CCT]5 CTT [TCT]4 CCT [TCT]27 |
40 | [CCT]5 CTT [TCT]4 CCT [TCT]29 |
+2 | |
|
|
|
|
|
|
|
| DYS635 | 23 | [TAGA]13 [TACA]2 [TAGA]2 [TACA]2 [TAGA]4 |
22 | [TAGA]12 [TACA]2 [TAGA]2 [TACA]2 [TAGA]4 |
−1 |
| 22 | [TAGA]12 [TACA]2 [TAGA]2 [TACA]2 [TAGA]4 |
23 | [TAGA]13 [TACA]2 [TAGA]2 [TACA]2 [TAGA]4 |
+1 | |
|
|
|
|
|
|
|
| DYS643 | 14 | [CTTTT]14 | 15 | [CTTTT]15 | +1 |
|
|
|
|
|
|
|
| Y-GATA-H4 | 11 | [TCTA]11 | 9 | [TCTA]9 | −2 |
| 12 | [TCTA]12 | 11 | [TCTA]11 | −1 | |
| 12 | [TCTA]12 | 13 | [TCTA]13 | + 1 | |
a
mutations reported at locus DYS389I were also observed at the encompassing DYS389II locus.
b
fathers exhibit likely somatic mutations at these loci which are not inherited to the next generation.
c
RM Y-STRs.