Table 1.
The characteristics of VOC
| VOC | Alpha variant | Beta variant | Gamma variant | Delta variant |
|---|---|---|---|---|
| Alternative name | 20I/501Y.V1 VOC202012/01 B.1.1.7 | 20H/501.V2 B.1.351 | 20C/S:452R CAL.20C P.1 | 20A/S:478K B.1.617.2 |
| First identification | September 2020 | October 2020 | January 2021 | October 2020 |
| Affected nations | UK 182 | South Africa 131 | Japan/Brazil 81 | India 132 |
| Transmissibility | Increase ﹥ 50% | Increase ﹥ 50% | Increase 40%–120% | Increase ﹥ 100% |
| Severity | Increased risk of hospitalization Increased fatality | Increased reinfection rate | Increased mortality Increased reinfection rate | Increased risk of hospitalization and deaths |
| Immunogenicity (neutralization antibody) | Mildly to moderately reduce Significantly reduce with E484K mutation | Significantly reduce | Moderately reduce | Moderately reduce |
| Reference | [3],[5],[70],[71],[72],[73],[74],[75] | [5],[75],[76],[77],[78] | [3],[5],[26],[75] [79],[80] | [5],[18],[22],[49],[63],[75], [81] |
VOC: variants of concern.