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. 2023 Jan 25;19(1):e1010610. doi: 10.1371/journal.pgen.1010610

Fig 2. Egg development requires mitochondrial oxidative phosphorylation.

Fig 2

(a) Schematic of an ovariole. An egg chamber is comprised of one oocyte, fifteen nurse cells and surrounding somatic follicle cells. Oogenesis comprises 14 stages resulting in the formation of a mature egg. (b-e) Representative images of Control (b), Complex II subunit D (c), Complex III Cyt-c1 (d) and Complex IV subunit 5A (e) mosaic ovarioles 14-days post-clone induction. Arrows indicate GFP-negative mutant cells. (f, g) Representative images of 2–3 day old Control (f) and germline expressed (nos-GAL4) Complex V dominant negative (DN) (g) in heterozygous CVc deficiency ovaries. (h) Representative image of a 2–3 day old bam-GAL4 driven CVα RNAi ovary. Arrows indicate the last stage observed in the representative ovariole. For all images scale bars represent 100 μm. For exact genotypes see S2 Table.