Table 4. Accuracy of detecting ion channel blocks from AP shape changes from computer simulation data using multi-class logistic regression.
Model | Overall Accuracy | INa Block (TTX) | IKr/INa Block (Flecainide) | ICa Block (Nifedipine) | IKr Block (E-4031) |
---|---|---|---|---|---|
Simulation Data | 0.9996 (6e-5) | 0.9994 (2e-4) | n/a | 0.9988 (3e-4) | 0.9999 (5e-5) |
Experimental Data | 0.95 (0.03) | 0.95 (0.07) | 0.94 (0.08) | 0.96 (0.06) | 0.96 (0.07) |