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. 2023 Feb 6;18(2):e0277213. doi: 10.1371/journal.pone.0277213

Table 1. Comparison of baseline characteristics of the participants.

Variable Synbiotic (n = 28) Placebo (n = 28) P-value
Age (year) 48.89 ± 9.45 46.07 ± 8.76 0.25
Weight (Kg) 75.15 ± 15.61 77.14 ± 17.16 0.65
Height (cm) 1.63 ± 0.07 1.63 ± 0.08 0.98
BMI (kg/cm 2 ) 28.05 ± 4.98 28.79 ± 5.30 0.59
Levothyroxine dose (μg) 77.51 ± 25.50 88.28 ± 21.12 0.10
Duration of Hypothyroidism (year) 9.50 ± 6.97 12.59 ± 10.69 0.21
Sex a Female 24 (85.7%) 23 (82.1%) 1.00
Male 4 (14.3%) 5 (17.9%)
Type of Hypothyroidism a Autoimmune 19 (79.2%) 19 (90.5%) 0.27
Non-autoimmune 5 (20.8%) 2 (9.5%)
Education Under diploma 8 (28.6%) 5 (17.9%) 0.36
Diploma 12 (42.9%) 10 (35.7%)
University 8 (28.6%) 13 (46.4%)
Marita Status a Married 23 (82.1%) 21 (75.0%) 0.88
Single 4 (14.3%) 4 (14.3%)
Divorced 0 (0.0%) 1 (3.6%)
Widowed 1 (3.6%) 2 (7.1%)
Vitamin-mineral supplement intake Yes 15 (53.6%) 14 (50.0%) 0.79
No 13 (46.4%) 14 (50.0%)

Independent sample t-test or chi-square test

a Two-tailed Fisher’s exact test

Mean ± SD or n (%)