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. 2023 Feb 6;23:73. doi: 10.1186/s12879-023-08024-2

Table 3.

Household-level out-of-pocket costs and payment sources (median, IQR), in 2022 US dollars

Cost components Outpatient Inpatient at RD ICU****
All
(N = 210)
RSV positive
(n = 21)
RSV negative
(n = 189)
p-value*** All
(N = 318)
RSV positive
(n = 84)
RSV negative
(n = 234)
p-value*** All RSV negatives
(n = 8)
Total out-of-pocket costs 51 (32–85) 52 (32–85) 51 (32–84) 0.71 112 (58–184) 117 (65–183) 110 (57–186) 0.45 543 (370–996)
(1) Direct medical costs 22 (13–32) 26 (16–32) 21 (12–32) 0.33 24 (13–49) 38 (20–61) 20 (12–37)  < 0.001 386 (161–813)
 Consultation fee 3 (2–4) 2 (2–3) 3 (2–4) 0.20 3 (2–6) 3 (2–6) 3 (2–5) 0.66 4 (2–6)
 Medication costs 15 (9–20) 15 (8–18) 15 (9–20) 0.49 3 (0–9) 6 (1–13) 2 (0–6)  < 0.001 33 (13–62)
 Laboratory costs 0 (0–2) 0 (0–2) 0 (0–0) 0.81 0 (0–2) 1 (0–3) 0 (0–2) 0.52 7 (0–45)
 Procedure & service cost 6 (3–11) 8 (4–13) 4 (3–11) 0.12 2 (0–16) 12 (6–23) 0 (0–13)  < 0.001 86 (30–311)
 Imaging costs 3 (3–5) 3 (3–3) 3 (3–5) 0.87 0 (0–3) 2 (1–5) 0 (0–2)  < 0.001 0 (0–4)
 Miscellaneous costs* 8 (1–13) 0 (0–0) 8 (1–13) 9 (3–18) 10 (4–18) 9 (2–18) 0.42 105 (79–158)
(2) Direct non-medical costs

5

(2–28)

4

(2–22)

5

(2–28)

0.82

35

(3–87)

27

(3–72)

38

(3–88)

0.57

76

(42–112)

 Transport costs 4 (2–27) 4 (2–22) 4 (2–27) 0.91 6 (2–28) 8 (2–41) 5 (1–24) 0.12 33 (3–78)
 Meal costs 0 (0–0) 0 (0–0) 0 (0–0) 0.18 32 (0–63) 2 (0–39) 41 (0–70)  < 0.001 5 (2–52)
 Accommodation costs 0 (0–0) 0 (0–0) 0 (0–0) N/A 0 (0–30) 0 (0–0) 16 (0–32)  < 0.001 10 (0–233)
 Caretaker costs 0 (0–0) 0 (0–0) 0 (0–0) N/A 6 (0–38) 47 (34–60) 0 (0–13) 0.08 0 (0–0)
(3) Indirect costs 11 (2–26) 22 (9–34) 9 (0–25) 0.09 19 (0–69) 18 (0–69) 20 (0–69) 0.93 85 (6–253)
 Lost income** 9 (0–25) 17 (9–34) 8 (0–22) 0.03 17 (0–69) 12 (0–68) 17 (0–69) 0.85 13 (4–194)
 Lost leisure** 6 (2–6) 3 (0–6) 6 (2–6) 0.18 2 (1–6) 6 (2–9) 2 (1–5) 0.05 3 (2–5)
Family response
 Reducing other expenses 34.3% 9.5% 37.0% 0.01 59.0% 42.9% 64.8% < 0.001 25.0%
 Use personal savings 87.1% 100.0% 85.7% 0.06 86.8% 94.1% 84.1% 0.02 100.0%
 Borrowed 2.4% 0.0% 2.7% 0.45 26.5% 6.0% 33.9% < 0.001 12.5%
 Selling assets 2.4% 4.8% 2.1% 0.45 5.7% 2.4% 6.9% 0.13 0.0%
 Donations 2.9% 0.0% 3.2% 0.41 16.4% 3.6% 21.0% < 0.001 0.0%
 Other 0% 0.0% 0.0% N/A 0.3% 0.0% 0.4% 0.55 0.0%

Total out-of-pocket costs = sum of (1–3). These costs were incurred prior to, during, and after hospitalization. (2) and (3) are the same as costs associated with the societal perspective in Table 2

*Miscellaneous costs include medical consumables such as syringes, gloves, and soap

**Opportunity costs of income lost due to missed work were based on the average salary reported by participants in the study, and opportunity costs of lost leisure time were based on the minimum Vietnamese income based on government data for the study period [18]

***Mann–Whitney U p-value comparing between the costs associated with RSV and those associated with no RSV

****No ICU cases were identified as RSV positive

ICU: intensive care unit; IQR: interquartile range; RD: Respiratory Department; RSV: respiratory syncytial virus