FIG 1.

Sixty-five year-old man with metastatic HPV-positive HNSCC. The images are computed tomography axial views of the locoregional and metastatic tumors in this patient. A (red circle), Left tonsil primary with significant regression after pembro-chemo. B (red circle), Left level IIA conglomerate nodal metastasis encasing and narrowing the external carotid artery; medially adjacent is the primary tumor. Treatment with pembro-chemo resulted in significant regression and increased patency of the external carotid artery. C (red arrows), Bilateral lung metastases with significant regression on pembro-chemo. HPV, human papilloma virus; HNSCC, head and neck squamous cell carcinoma; pembro-chemo, pembrolizumab-chemotherapy.